MLB predictions, odds, picks for Tuesday, July 21: This 3-way parlay returns over +800 - CBS Sports
Key Matchups and Player Performances
Tuesday’s MLB schedule features several compelling matchups, with particular attention on player props and team advantages. The game between the New York Mets and the Milwaukee Brewers highlights Bo Bichette’s recent performance. Despite a challenging season with the Mets, Bichette has shown improvement, recording two two-hit games in his last two appearances. He is striking out at a lower rate over his recent plate appearances. His matchup against Brandon Sproat, who has displayed reverse splits and a higher wOBA against right-handed hitters, could be significant for Bichette.
In the game between the Detroit Tigers and the Chicago Cubs, Spencer Torkelson is a player to watch. Torkelson, who had a strong 2025 season, has maintained a career-best hard-hit rate this season. He has been particularly effective against left-handed pitchers, posting a strong wOBA and fly-ball rate. His performance against David Peterson, who has faced difficulties with the Cubs, could be a key factor in the game. Peterson has struggled with a high SIERA and home run rate, especially in one particular start at Wrigley.

The Cincinnati Reds versus Seattle Mariners game features Chase Burns, known for his strikeout ability. T-Mobile Park, where the game is being played, has been identified as a pitcher-friendly venue, particularly for strikeouts, over the past three seasons. Burns has a high strikeout rate and swinging-strike rate, and he has recorded multiple games with at least eight strikeouts in his recent starts. The Mariners also present a favorable matchup for strikeouts, given their high team K rate and lower wOBA.
Team Advantages and Betting Insights
The Reds at Mariners game presents a strong starting pitching advantage for Cincinnati with rookie right-hander Chase Burns. Burns has compiled an 11-1 record with a 2.54 ERA and 1.11 WHIP, along with 118 strikeouts over 102.2 innings. His consistent performance and elite swing-and-miss capabilities make him a dominant force. The Mariners will counter with Luis Castillo, who has a 3-8 record, 4.93 ERA, and 1.37 WHIP over 87.2 innings this season. While Seattle has a 51-50 overall record and a 30-21 home record, they have cooled recently, going 4-6 in their last ten games. Cincinnati, with a 45-54 record and 23-26 on the road, also has a 4-6 record in their last ten games but possesses offensive firepower with players like Elly De La Cruz and Sal Stewart.
In the Miami Marlins versus Houston Astros matchup, Miami appears to have an advantage in several statistical categories. The Marlins hold a 52-49 overall record compared to Houston’s 48-54. Tyler Phillips, a steady starter for Miami, has a 3.48 ERA and 1.39 WHIP over 75 innings. Houston’s Tatsuya Imai has a 6.06 ERA and 1.50 WHIP over 52 innings, struggling with command despite strikeout potential. Miami also has a stronger overall statistical profile with a 4.05 team ERA compared to Houston’s 4.75, and advantages in batting average, on-base percentage, and OPS. Both teams have a 3-7 record in their last ten games, but Miami has been the more consistent team throughout the season and ranks among the best baserunning teams with 104 stolen bases.
Underdog Opportunities
The Tigers at Cubs game offers an underdog opportunity for Detroit. The Tigers have a significant edge on the mound with Framber Valdez, a veteran left-hander with a 5-6 record, 4.10 ERA, and 1.32 WHIP over 107.2 innings. His underlying metrics are stronger than his record suggests, and he is known for generating weak contact. Chicago’s David Peterson has struggled with a 6.45 ERA and 1.64 WHIP across 82.1 innings, allowing frequent baserunners. While the Cubs have a 56-44 overall record, Detroit is playing strong baseball, with a 7-3 record in their last ten games and a 2.10 team ERA. The Tigers also have a better season-long team ERA of 3.59 compared to Chicago’s 4.29, and have allowed fewer home runs.
Considering the pitching advantages, the Reds are seen as a value play at +107 against the Mariners. The Marlins also present value at +108 against the Astros due to their overall team strength and pitching matchup. The Tigers, with Framber Valdez on the mound, are considered a strong bet at +105 against the Cubs, especially given their recent form and superior pitching staff.
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Source: fanduel.com